Relationship between plasma plasminogen activator inhibitor-1 and hypertension in American Indians
Abstract
Objectives: Deficient plasminogen activator inhibitor-1 (PAI-1) prevented hypertension in mice. Plasma PAI-1 was associated with hypertension in cross-sectional analyses, but the prospective association of PAI-1 with incident hypertension in large epidemiological studies is scarce. Methods: Leveraging two longitudinal cohorts of American Indians in the Strong Heart Study (SHS, N = 1019) and the Strong Heart Family Study (SHFS, N = 1502), we...
Paper Details
Title
Relationship between plasma plasminogen activator inhibitor-1 and hypertension in American Indians
Published Date
Sep 1, 2017
Journal
Volume
35
Issue
9
Pages
1787 - 1793
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