Neuronal cells derived from human induced pluripotent stem cells as a functional tool of melanocortin system

The preparation of human neurons derived from human induced pluripotent stem (iPS) cells can serve as a potential tool for evaluating the physiological and pathophysiological properties of human neurons and for drug development. In the present study, the functional activity in neuronal cells differentiated from human iPS cells was observed. The differentiated cells expressed mRNAs for classical neuronal markers (microtubule-associated protein 2,...