Inhibition of neuronal ferroptosis protects hemorrhagic brain
Abstract
Intracerebral hemorrhage (ICH) causes high mortality and morbidity, but our knowledge of post-ICH neuronal death and related mechanisms is limited. In this study, we first demonstrated that ferroptosis, a newly identified form of cell death, occurs in the collagenase-induced ICH model in mice. We found that administration of ferrostatin-1, a specific inhibitor of ferroptosis, prevented neuronal death and reduced iron deposition induced by...
Paper Details
Title
Inhibition of neuronal ferroptosis protects hemorrhagic brain
Published Date
Apr 6, 2017
Journal
Volume
2
Issue
7
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