Protective effect of nordihydroguaiaretic acid (NDGA) on the transgenic Drosophila model of Alzheimer's disease
Abstract
• AD flies were exposed to 20, 40, 60 and 80 μM of NDGA for 30 days. • NDGA results in an increased life span and delayed the loss of climbing ability. • NDGA prevents the memory loss and reduced the oxidative stress in the brain of AD flies. • NDGA did not influence the expression/aggregation of...
Paper Details
Title
Protective effect of nordihydroguaiaretic acid (NDGA) on the transgenic Drosophila model of Alzheimer's disease
Published Date
May 1, 2017
Volume
269
Pages
59 - 66
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