The role of SIRT1 in diabetic cardiomyopathy
Abstract
The prevalence of diabetes mellitus (DM) has been increasing worldwide. Diabetic cardiomyopathy (DCP) is the major risk for diabetes associated morbidity and mortality. Hyperglycemia and hyperinsulinemia play an indispensable role in underlying mechanisms of DCP. They increase advanced glycation end products (AGEs) following a series of events leading to myocardial damage and cardiomyopathy which include oxidative stress, increased inflammation,...
Paper Details
Title
The role of SIRT1 in diabetic cardiomyopathy
Published Date
Jun 1, 2017
Volume
90
Pages
386 - 392
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