Investigation of chronic toxicity of hydroxyapatite nanoparticles administered orally for one year in wistar rats

Volume: 76, Pages: 518 - 527
Published: Jul 1, 2017
Abstract
Although the toxicity/biocompatibility of hydroxyapatite nanoparticles (nano HA), a prospective nano biomaterial is extensively studied, its interaction on biological systems following chronic exposure is less exploited. In the present study, Wistar rats were given various concentrations of nano HA in the diet to determine the chronic toxicity and potential carcinogenicity. Altogether 140 rats were used for the study under various administration...
Paper Details
Title
Investigation of chronic toxicity of hydroxyapatite nanoparticles administered orally for one year in wistar rats
Published Date
Jul 1, 2017
Volume
76
Pages
518 - 527
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