Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation
Abstract
Purpose The major causes of mortality after allogeneic hematopoietic-cell transplantation (allo-HCT) are relapse, graft-versus-host disease (GVHD), and infection. We have reported previously that alterations in the intestinal flora are associated with GVHD, bacteremia, and reduced overall survival after allo-HCT. Because intestinal bacteria are potent modulators of systemic immune responses, including antitumor effects, we hypothesized that...
Paper Details
Title
Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation
Published Date
Mar 15, 2017
Journal
Volume
35
Issue
15
Pages
1650 - 1659
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Notes
History