Telomeres and Cell Senescence - Size Matters Not
Abstract
null Telomeres are protective structures present at the ends of linear chromosomes that are important in preventing genome instability. Telomeres shorten as a result of cellular replication, leading to a permanent cell cycle arrest, also known as replicative senescence. Senescent cells have been shown to accumulate in mammalian tissue with age and in a number of age-related diseases, suggesting that they might contribute to the loss of tissue...
Paper Details
Title
Telomeres and Cell Senescence - Size Matters Not
Published Date
Jul 1, 2017
Journal
Volume
21
Pages
14 - 20
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