Original paper
The electric fence to cell-cycle progression: Do local changes in membrane potential facilitate disassembly of the primary cilium?
Abstract
Kv10.1 is a voltage‐gated potassium channel relevant for tumor biology, but the underlying mechanism is still unclear. We propose that Kv10.1 plays a role coordinating primary cilium disassembly with cell cycle progression through localized changes of membrane potential at the ciliary base. Most non‐dividing cells display a primary cilium, an antenna‐like structure important for cell physiology. The cilium is disassembled when the cell divides,...
Paper Details
Title
The electric fence to cell-cycle progression: Do local changes in membrane potential facilitate disassembly of the primary cilium?
Published Date
Mar 30, 2017
Journal
Volume
39
Issue
6
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Notes
History