Polymorphism, pseudo-polymorphism, and conformerism in the crystal structure of piperazine-N,N′-bis(N,O-diphenyl phosphoramidate)

Herein, we report on the synthesis of a novel bisphosphoramidate compound (LOPhAn), (C6H5O)(C6H5NH)P(O)NC4H8N(O)P(OC6H5)(NHC6H5), with two polymorphic (I and III) and one methanol solvated pseudo-polymorphic (II.MeOH) structures in the solid state obtained by crystal growth from different solvents. Single crystal X-ray analysis revealed that Form (I) has one extended conformer of LOPhAn in the solid state, while Form (II) demonstrated one...