Resistance mutations of hepatitis B virus in entecavir-refractory patients.

Volume: 1, Issue: 2, Pages: 110 - 121
Published: Mar 9, 2017
Abstract
The emergence of resistance mutations in the reverse transcriptase gene of hepatitis B virus (HBV) is associated with treatment failure. Entecavir (ETV) is one of the most potent anti-HBV reagents; it has a very low resistance rate and is used as the first-line treatment for chronic hepatitis B. In this study, we isolated HBVs in 4 ETV-refractory patients (2 with viral breakthrough, 1 with partial virological response, and 1 with flare-up) and...
Paper Details
Title
Resistance mutations of hepatitis B virus in entecavir-refractory patients.
Published Date
Mar 9, 2017
Volume
1
Issue
2
Pages
110 - 121
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