Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population
Volume: 118, Issue: 4, Pages: 483 - 488.e1
Published: Apr 1, 2017
Abstract
Background Allergic asthma is a complex disorder that results from a combination of genetic and environmental factors. Studies suggest that helminth infections can activate a regulatory network characterized by the production of regulatory cytokines, such as interleukin 10 and transforming growth factor β1 (TGF-β1) and subsequently protect against immune-mediated diseases, such as asthma. On the other hand, TGF-β1 is increased in the lungs of...
Paper Details
Title
Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population
Published Date
Apr 1, 2017
Volume
118
Issue
4
Pages
483 - 488.e1
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