Protein Complexes in the Nucleus: The Control of Chromosome Segregation

Volume: 83, Pages: 455 - 481
Published: Jan 1, 2017
Abstract
Mistakes in the process of cell division can lead to the loss, gain or rearrangement of chromosomes. Significant chromosomal abnormalities are usually lethal to the cells and cause spontaneous miscarriages. However, in some cases, defects in the spindle assembly checkpoint lead to severe diseases, such as cancer and birth and development defects, including Down’s syndrome. The timely and accurate control of chromosome segregation in mitosis...
Paper Details
Title
Protein Complexes in the Nucleus: The Control of Chromosome Segregation
Published Date
Jan 1, 2017
Volume
83
Pages
455 - 481
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