Evidence for neuroplastic compensation in the cerebral cortex of persons with depressive illness

Volume: 23, Issue: 2, Pages: 375 - 383
Published: Mar 7, 2017
Abstract
We yoked anatomical brain magnetic resonance imaging to a randomized, double-blind, placebo-controlled trial (RCT) of antidepressant medication for 10-week’s duration in patients with dysthymia. The RCT study design mitigated ascertainment bias by randomizing patients to receive either duloxetine or placebo, and it supported true causal inferences about treatment effects on the brain by controlling treatment assignment experimentally. We...
Paper Details
Title
Evidence for neuroplastic compensation in the cerebral cortex of persons with depressive illness
Published Date
Mar 7, 2017
Volume
23
Issue
2
Pages
375 - 383
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