Clinical relevance of hypercoagulability and possible hypofibrinolysis associated with estrone and estriol

Estrone (E 1 ) and Estriol (E 3 ) are endogenous female hormones, present in increased concentrations during female specific physiological processes (menopause and pregnancy respectively) that are associated with increased venous thrombotic risk. These hormones are also used as hormone therapies that are also associated with increased thromboembolism risk. Viscoelastic analysis revealed no significant difference to clot formation after hormone...