Original paper
Synthetic Biomarker Design by Using Analyte‐Responsive Acetaminophen
Abstract
The use of synthetic biomarkers is an emerging technique to improve disease diagnosis. Here, we report a novel design strategy that uses analyte‐responsive acetaminophen (APAP) to expand the catalogue of analytes available for synthetic biomarker development. As proof‐of‐concept, we designed hydrogen peroxide (H 2 O 2 )‐responsive APAP (HR‐APAP) and succeeded in H 2 O 2 detection with cellular and animal experiments. In fact, for blood samples...
Paper Details
Title
Synthetic Biomarker Design by Using Analyte‐Responsive Acetaminophen
Published Date
Apr 4, 2017
Journal
Volume
18
Issue
10
Pages
910 - 913
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Notes
History