Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects
Abstract
Limiting the debilitating consequences of ageing is a major medical challenge of our time. Robust pharmacological interventions that promote healthy ageing across diverse genetic backgrounds may engage conserved longevity pathways. Here we report results from the Caenorhabditis Intervention Testing Program in assessing longevity variation across 22 Caenorhabditis strains spanning 3 species, using multiple replicates collected across three...
Paper Details
Title
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects
Published Date
Feb 21, 2017
Journal
Volume
8
Issue
1
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