The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV
Abstract
The interactions that occur during HIV Pr55Gag oligomerization and genomic RNA packaging are essential elements that facilitate HIV assembly. However, mechanistic details of these interactions are not clearly defined. Here, we overcome previous limitations in producing large quantities of full-length recombinant Pr55Gag that is required for isothermal titration calorimetry (ITC) studies, and we have revealed the thermodynamic properties of HIV...
Paper Details
Title
The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV
Published Date
Feb 21, 2017
Journal
Volume
13
Issue
2
Pages
e1006221 - e1006221
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