Targeting Splicing in the Treatment of Human Disease
Abstract
The tightly regulated process of precursor messenger RNA (pre-mRNA) alternative splicing (AS) is a key mechanism in the regulation of gene expression. Defects in this regulatory process affect cellular functions and are the cause of many human diseases. Recent advances in our understanding of splicing regulation have led to the development of new tools for manipulating splicing for therapeutic purposes. Several tools, including antisense...
Paper Details
Title
Targeting Splicing in the Treatment of Human Disease
Published Date
Feb 24, 2017
Journal
Volume
8
Issue
3
Pages
87 - 87
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History