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Physical Activity Is Related with Cartilage Quality in Women with Knee Osteoarthritis

Published on Jul 1, 2017in Medicine and Science in Sports and Exercise4.478
· DOI :10.1249/MSS.0000000000001238
Matti Munukka4
Estimated H-index: 4
(University of Jyväskylä),
Benjamin Waller9
Estimated H-index: 9
(University of Jyväskylä)
+ 7 AuthorsAri Heinonen55
Estimated H-index: 55
(University of Jyväskylä)
Sources
Abstract
ABSTRACTPurposeTo study the relationship between 12-month leisure-time physical activity (LTPA) level and changes in estimated biochemical composition of tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis (OA).MethodsOriginally, 87 volunteer postmenopausal women, age 60 to
  • References (40)
  • Citations (5)
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References40
Newest
#1Matti Munukka (University of Jyväskylä)H-Index: 4
#2Benjamin Waller (University of Jyväskylä)H-Index: 9
Last. Ari Heinonen (University of Jyväskylä)H-Index: 55
view all 14 authors...
Summary Objective To study the efficacy of aquatic resistance training on biochemical composition of tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis (OA). Design Eighty seven volunteer postmenopausal women, aged 60–68 years, with mild knee OA (Kellgren–Lawrence grades I/II and knee pain) were recruited and randomly assigned to an intervention ( n = 43) and control ( n = 44) group. The intervention group participated in 48 supervised aquatic resistance training sessio...
13 CitationsSource
#1Zana Hawezi (Lund University)H-Index: 3
#2Eveliina Lammentausta (OUH: Oulu University Hospital)H-Index: 17
Last. Carl Johan Tiderius (Lund University)H-Index: 18
view all 6 authors...
Previously, a positive effect of exercise on cartilage structure was indicated with delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC). However, in that study only one full-thickness region of interest (ROI) in the medial femoral condyle was analyzed.
6 CitationsSource
#1Marlene Fransen (USYD: University of Sydney)H-Index: 38
#2Sara McConnellH-Index: 11
Last. Kim L. Bennell (RMIT: RMIT University)H-Index: 80
view all 6 authors...
Objective To determine whether land-based therapeutic exercise is beneficial for people with knee osteoarthritis (OA) in terms of reduced joint pain or improved physical function and quality of life. Methods Five electronic databases were searched, up until May 2013. Randomised clinical trials comparing some form of land-based therapeutic exercise with a non-exercise control were selected. Three teams of two review authors independently extracted data and assessed risk of bias for each study. St...
164 CitationsSource
AB Purpose: This study aims to investigate the effects of exercise on patellar cartilage using T2 relaxation time mapping of magnetic resonance imaging in postmenopausal women with mild patellofemoral joint osteoarthritis (OA). Methods: Eighty postmenopausal women (mean age, 58 (SD, 4.2) yr) with mild knee OA were randomized to either a supervised progressive impact exercise program three times a week for 12 months (n = 40) or a nonintervention control group (n = 40). Biochemical properties of c...
17 CitationsSource
#1Benjamin Waller (University of Jyväskylä)H-Index: 9
Last. Ari Heinonen (University of Jyväskylä)H-Index: 55
view all 7 authors...
Background Current management of osteoarthritis (OA) focuses on pain control and maintaining physical function through pharmacological, nonpharmacological, and surgical treatments. Exercise, including therapeutic aquatic exercise (TAE), is considered one of the most important management options. Nevertheless, there is no up-to-date systematic review describing the effect of TAE on symptoms and function associated with lower limb OA. Purpose The purpose of this study was to conduct a systematic r...
37 CitationsSource
#1Timothy E. McAlindon (Tufts Medical Center)H-Index: 57
#2Raveendhara R. Bannuru (Tufts Medical Center)H-Index: 20
Last. Martin Underwood (Coventry Health Care)H-Index: 46
view all 15 authors...
Objective: To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide. Method: Thirteen experts from relevant medical disciplines (primary care, rheumatology, orthopedics, physical therapy, physical medicine and rehabilitation, and evidence-based medicine), three continents and ten countries (USA, UK, France, Netherlands, Belgium...
1,154 CitationsSource
#1Victoria L. Johnson (USYD: University of Sydney)H-Index: 5
#2David H. Hunter (RNSH: Royal North Shore Hospital)H-Index: 184
Abstract Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to increasing obesity and an ageing population. Risk factors can be divided into person-level factors, such as age, sex, obesity, genetics, race/ethnicity and diet, and joint-level factors including injury, malalignment and abnormal loading of the joints. The interaction of these risk factors is complex and provides a challenge to the managing physician. The purpose of this review is to illustrate how e...
295 CitationsSource
Osteoarthritis and osteoporosis often coexist in postmenopausal women. The simultaneous effect of bone-favorable high-impact training on these diseases is not well understood and is a topic of controversy. We evaluated the effects of high-impact exercise on bone mineral content (BMC) and the estimated biochemical composition of knee cartilage in postmenopausal women with mild knee osteoarthritis. Eighty women aged 50 to 66 years with mild knee osteoarthritis were randomly assigned to undergo sup...
32 CitationsSource
#1June E. Jeon (QUT: Queensland University of Technology)H-Index: 7
#2Karsten Schrobback (QUT: Queensland University of Technology)H-Index: 13
Last. Travis J. Klein (QUT: Queensland University of Technology)H-Index: 32
view all 6 authors...
Objective One of the pathologic changes that occurs during osteoarthritis (OA) is the degeneration of the pericellular matrix (PCM). Since the PCM is likely to be involved in mechanotransduction, this study was undertaken to investigate the effects of PCM-like matrix accumulation in zonal OA chondrocytes and their influence on chondrocyte response to compression. Methods Superficial and middle/deep zone chondrocytes from macroscopically normal cartilage of OA knees were expanded and encapsulated...
20 CitationsSource
#1Benjamin Waller (University of Jyväskylä)H-Index: 9
#2Matti Munukka (University of Jyväskylä)H-Index: 4
Last. Ari Heinonen (University of Jyväskylä)H-Index: 55
view all 14 authors...
Background Symptoms associated with osteoarthritis of the knee result in decreased function, loss of working capacity and extensive social and medical costs. There is a need to investigate and develop effective interventions to minimise the impact of and even prevent the progression of osteoarthritis. Aquatic exercise has been shown to be effective at reducing the impact of osteoarthritis. The purpose of this article is to describe the rationale, design and intervention of a study investigating ...
21 CitationsSource
Cited By5
Newest
#1J.J. Bjerre-Bastos (UCPH: University of Copenhagen)
#2Morten KarsdalH-Index: 2
Last. A. Bihlet (UCPH: University of Copenhagen)H-Index: 9
view all 7 authors...
Source
#1Matti Munukka (University of Jyväskylä)H-Index: 4
#2Benjamin Waller (University of Jyväskylä)H-Index: 9
Last. Ari Heinonen (University of Jyväskylä)H-Index: 55
view all 10 authors...
OBJECTIVE: To conduct a secondary analysis to study the effects, those 4 months of aquatic resistance training have on self-assessed symptoms and quality of life in post-menopausal women with mild knee osteoarthritis (OA), after the intervention and after a 12-month follow-up period. METHODS: A total of 87 post-menopausal volunteer women, aged 60-68 years, with mild knee OA were recruited in a randomized, controlled, 4-month aquatic training trial (RCT) and randomly assigned to an intervention (...
Source
#1Sirous Azizi (Aja University of Medical Sciences)
#2Afsaneh Dadarkhah (Aja University of Medical Sciences)H-Index: 1
Last. Sharif Najafi (Aja University of Medical Sciences)H-Index: 1
view all 6 authors...
AimThe aim of this study is to assess the efficacy of aquatic exercise on pain, gait, and balance among elderly patients with knee osteoarthritis.MethodsWe performed a randomized controlled trial a...
Source
#1Alessio BriccaH-Index: 3
#2Carsten Bogh JuhlH-Index: 17
Last. Ewa M. RoosH-Index: 65
view all 5 authors...
Objective To investigate the impact of knee joint loading exercise on articular cartilage in people at risk of, or with established, knee osteoarthritis (OA) by conducting a systematic review of randomised controlled trials (RCTs). Design We followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Data sources We performed a literature search with no restriction on publication year or language in MEDLINE, EMBASE, CINAHL, the Cochrane Central Register of Control...
13 CitationsSource
#1Zhengping HuangH-Index: 2
#2Changhai Ding (Southern Medical University)H-Index: 45
Last. Shirley Pei-Chun Yu (RNSH: Royal North Shore Hospital)H-Index: 4
view all 4 authors...
OA is a chronic, progressive and disabling joint disease, leading to a poor quality of life and an enormous social and economic burden. Current therapies for OA patients remain limited, which creates an area of huge unmet medical need. For some time, researchers have been looking for approaches that can inhibit the structural progression of OA. A variety of potential disease-modifying OA drugs have been developed, targeting cartilage, inflammatory pathways or subchondral bone. In addition, non-p...
2 CitationsSource
#1Linda C. LiH-Index: 17
#2Eric C. SayreH-Index: 21
Last. Lynne M. FeehanH-Index: 9
view all 10 authors...
Background: Current practice guidelines emphasize the use of physical activity as the first-line treatment of knee osteoarthritis; however, up to 90% of people with osteoarthritis are inactive. Objective: We aimed to assess the efficacy of a technology-enabled counseling intervention for improving physical activity in people with either a physician-confirmed diagnosis of knee osteoarthritis or having passed two validated criteria for early osteoarthritis. Methods: We conducted a proof-of-concept...
5 CitationsSource
#1Benjamin WallerH-Index: 9
#2Matti MunukkaH-Index: 4
Last. Ari HeinonenH-Index: 55
view all 4 authors...
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