ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.

Volume: 25, Issue: 7, Pages: 1000 - 1009
Published: Jul 1, 2017
Abstract
Summary null Introduction null Matrix metalloproteinases (MMPs) and ‘aggrecanase' a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) are well established to play key roles in osteoarthritis (OA) through degradation of extracellular matrix (ECM) type II collagen and aggrecan, and are thus potential targets for development of OA therapies. null Objective null This paper aims to provide a comprehensive review of the expression...
Paper Details
Title
ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.
Published Date
Jul 1, 2017
Volume
25
Issue
7
Pages
1000 - 1009
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