A large-scale evaluation of algorithms to calculate average nucleotide identity
Abstract
Average nucleotide identity (ANI) is a category of computational analysis that can be used to define species boundaries of Archaea and Bacteria. Calculating ANI usually involves the fragmentation of genome sequences, followed by nucleotide sequence search, alignment, and identity calculation. The original algorithm to calculate ANI used the BLAST program as its search engine. An improved ANI algorithm, called OrthoANI, was developed to...
Paper Details
Title
A large-scale evaluation of algorithms to calculate average nucleotide identity
Published Date
Feb 15, 2017
Journal
Volume
110
Issue
10
Pages
1281 - 1286
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