Mechanical stretch triggers rapid epithelial cell division through Piezo1
Abstract
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body. However, epithelial cell division must be tightly linked to cell death to preserve barrier function and prevent tumour formation. How does the number of dying cells match those dividing to maintain constant numbers? When epithelial cells become too crowded, they activate the stretch-activated channel Piezo1 to trigger...
Paper Details
Title
Mechanical stretch triggers rapid epithelial cell division through Piezo1
Published Date
Feb 15, 2017
Journal
Volume
543
Issue
7643
Pages
118 - 121
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Notes
History