A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Abstract
Antimicrobial peptides (AMPs) are promising candidates for the development of novel antibiotics, but it is difficult to produce sufficient quantities for preclinical and clinical studies due to their toxicity towards microbial expression hosts. To avoid laborious trial-and-error testing for the identification of suitable expression constructs, we have developed a small-scale expression screening platform based on a combinatorial plasmid...
Paper Details
Title
A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Published Date
Feb 13, 2017
Journal
Volume
16
Issue
1
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