Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
Abstract
Flow chemistry enables the preparation of bis(indolyl)methanes from various indoles and structurally divergent aldehydes using Sc(OTf)3 catalysis. The reaction is regioselective for C-3 functionalization of the indoles, occurring over short reaction times allowing for rapid investigation of scope with straightforward work up facilitating product...
Paper Details
Title
Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
Published Date
Apr 1, 2017
Journal
Volume
73
Issue
14
Pages
1812 - 1819
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