Bioengineering Hearts: Simple yet Complex

In this review, we focus on the multiple advancements in the field of cardiovascular regenerative medicine and the state-of-the art of building a heart. An organ is comprised of cells, but cells alone do not comprise an organ. We summarize the components needed, the hurdles, and likely translational steps defining the opportunities for discovery. The therapies being developed in regenerative medicine aim not only to repair, but also to...