Euglenophycin is produced in at least six species of euglenoid algae and six of seven strains of Euglena sanguinea

Published on Mar 1, 2017in Harmful Algae 4.14
· DOI :10.1016/j.hal.2017.01.010
Paul V. Zimba26
Estimated H-index: 26
(Texas A&M University–Corpus Christi),
I-Shuo Huang3
Estimated H-index: 3
(Texas A&M University–Corpus Christi)
+ 3 AuthorsRichard E. Triemer25
Estimated H-index: 25
(Michigan State University)
Abstract
Abstract Euglena sanguinea is known to produce the alkaloid toxin euglenophycin and is known to cause fish kills and inhibit mammalian tissue and microalgal culture growth. An analysis of over 30 species of euglenoids for accumulation of euglenophycin identified six additional species producing the toxin; and six of the seven E. sanguinea strains produced the toxin. A phylogenetic assessment of these species confirmed most taxa were in the Euglenaceae, whereas synthesis capability apparently has been lost in the Phacus, Eutreptiella, and Discoplastis branches.
  • References (35)
  • Citations (5)
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References35
Published on Jan 1, 2005in Journal of Organic Chemistry 4.80
W.E.A. Kardinaal1
Estimated H-index: 1
,
Petra M. Visser33
Estimated H-index: 33
+ 1 AuthorsH.C.P. Matthijs32
Estimated H-index: 32
48 Citations
Published on Aug 1, 2008in Aquaculture 2.71
Juliette L. Smith6
Estimated H-index: 6
(State University of New York System),
Greg L. Boyer1
Estimated H-index: 1
(State University of New York System),
Paul V. Zimba26
Estimated H-index: 26
(United States Department of Agriculture)
Increased demand has pushed extensive aquaculture towards intensively operated production systems, commonly resulting in eutrophic conditions and cyanobacterial blooms. This review summarizes those cyanobacterial secondary metabolites that can cause undesirable tastes and odors (odorous metabolites) or are biochemically active (bioactive metabolites) in marine and freshwater, extensive and intensive aquaculture systems. For the scope of this paper, biochemically active metabolites include (1) to...
181 Citations Source Cite
Published on Aug 1, 2012in Nature Methods 26.92
Diego Darriba7
Estimated H-index: 7
,
Guillermo L. Taboada14
Estimated H-index: 14
+ 1 AuthorsDavid Posada50
Estimated H-index: 50
5,840 Citations Source Cite
Published on Sep 1, 2006in African Journal of Marine Science 0.89
JoAnn M. Burkholder55
Estimated H-index: 55
,
Patricia M. Glibert58
Estimated H-index: 58
Intraspecific variability (strain differences) in key characteristics such as life-history traits, behaviour, nutrition, genetics and toxicity, has been experimentally documented for many toxigenic microalgae, including species of cyanobacteria, dinoflagellates, haptophytes, raphidophytes and diatoms. This paper summarises findings from published studies on intraspecific variability in toxicity. The data show that different, often opposite, interpretations at the species level would have resulte...
41 Citations Source Cite
Published on Jan 1, 2010in Toxicon 2.35
Paul V. Zimba26
Estimated H-index: 26
(Agricultural Research Service),
Peter D. R. Moeller21
Estimated H-index: 21
(National Oceanic and Atmospheric Administration)
+ 2 AuthorsRichard E. Triemer25
Estimated H-index: 25
(Michigan State University)
Abstract Currently cyanoprokaryotic algae, diatoms, haptophytes, dinoflagellates, euglenoids, and rhaphidophytes are known to produce algal toxins. A previous study by the authors reported euglenoid algae producing toxin(s) in aquaculture ponds, with confirmation based on positive fish bioassays following exposure to the isolated clonal algal cultures. Toxicity was observed in euglenoid culture isolates obtained from the pond as well as a clonal, culture collection taxon. Here we provide conclus...
31 Citations Source Cite
Published on Oct 1, 1972in Antimicrobial Agents and Chemotherapy 4.26
D. P. Jouvenaz1
Estimated H-index: 1
(United States Department of Agriculture),
M. S. Blum1
Estimated H-index: 1
,
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Estimated H-index: 1
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55 Citations Source Cite
Published on Mar 1, 1999in Estuaries
Michael B. Kingston3
Estimated H-index: 3
(Duke University)
Two benthic microalgal species, Euglena proxima (Dangeard) and the diatom Hantzschia virgata var. intermedia (Grun) Round, congregated at the sediment surface of intertidal sand flats surrounding the Duke University Marine Laboratory in Beaufort, North Carolina, during low tide and migrated below the surface prior to tidal flooding. E. proxima was found down to a depth of 12 cm below the surface during high tide while H. virgata was not found below 8 cm. One potential advantage of vertical migra...
31 Citations Source Cite
Published on Dec 1, 2013in Nature Communications 12.35
William M. Durham10
Estimated H-index: 10
,
Eric Climent20
Estimated H-index: 20
+ 4 AuthorsRoman Stocker37
Estimated H-index: 37
Patchiness plays a fundamental role in phytoplankton ecology by dictating the rate at which individual cells encounter each other and their predators. The distribution of motile phytoplankton species is often considerably more patchy than that of non-motile species at submetre length scales, yet the mechanism generating this patchiness has remained unknown. Here we show that strong patchiness at small scales occurs when motile phytoplankton are exposed to turbulent flow. We demonstrate experimen...
83 Citations Source Cite
Published on Dec 26, 2014in Marine Drugs 4.38
Paul G. Wahome3
Estimated H-index: 3
,
Kevin R. Beauchesne5
Estimated H-index: 5
+ 4 AuthorsPeter D. R. Moeller21
Estimated H-index: 21
(National Oceanic and Atmospheric Administration)
Aquatic microbes produce diverse secondary metabolites with interesting biological activities. Cytotoxic metabolites have the potential to become lead compounds or drugs for cancer treatment. Many cytotoxic compounds, however, show undesirable toxicity at higher concentrations. Such undesirable activity may be reduced or eliminated by using lower doses of the cytotoxic compound in combination with another compound that modulates its activity. Here, we have examined the cytotoxicity of four micro...
4 Citations Source Cite
Published on Jan 1, 2011in Harmful Algae 4.14
Birger Skjelbred9
Estimated H-index: 9
(University of Oslo),
Tor Einar Horsberg20
Estimated H-index: 20
(Norwegian University of Life Sciences)
+ 2 AuthorsBente Edvardsen27
Estimated H-index: 27
(University of Oslo)
Abstract Recurrent blooms of the marine flagellate genus Pseudochattonella have caused several fish kills in Northern Europe and Japan during the last two decades. Six different bioassays using fish cells, fish and brine shrimp nauplii were assessed as test systems for investigating ichthyotoxic mechanisms of Pseudochattonella . Metabolic activity in embryo cells from chinook salmon (CHSE-214) was inhibited in 2 strains, increased in another strain but was unaffected in a further 2 strains when ...
22 Citations Source Cite
Cited By5
Published on Jun 1, 2018in Journal of Applied Phycology 2.40
Agata Kulczycka (University of Warsaw), Maja Łukomska‐Kowalczyk3
Estimated H-index: 3
(University of Warsaw)
+ 1 AuthorsRafał Milanowski10
Estimated H-index: 10
(University of Warsaw)
Euglena sanguinea Ehrenberg is the only known species of euglenids which forms toxic blooms causing tangible losses to fish farms. Euglena sanguinea produces euglenophycin, a toxin similar in structure to solenopsin, an alkaloid found in fire ant venom. It was proved that euglenophycin exhibits not only ichthyotoxic but also herbicidal and anticancer activity. Recently, a specific mass spectrometric method of identification and quantitation of euglenophycin was developed to facilitate monitoring...
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Published on Mar 1, 2018in Marine Pollution Bulletin 3.24
Monique Nunes1
Estimated H-index: 1
,
J.B. Adams25
Estimated H-index: 25
,
Gavin M. Rishworth8
Estimated H-index: 8
(DST Systems)
Abstract Hydrological regimes are key in shaping the structure of phytoplankton communities in estuaries. Because anthropogenic disturbances often alter the quantity and quality of riverine inputs, this research focused on investigating phytoplankton dynamics in the St. Lucia Estuary, since being reconnected to the Mfolozi River. Due to the closed mouth state of the estuary, the input from the river resulted in oligohaline (≥5) conditions and the characteristic reverse salinity gradient to persi...
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Published on Mar 1, 2018in Harmful Algae 4.14
Yeong Du Yoo26
Estimated H-index: 26
(Kunsan National University),
Kyeong Ah Seong19
Estimated H-index: 19
(Kunsan National University)
+ 6 AuthorsBrian Palenik41
Estimated H-index: 41
(University of California, San Diego)
Abstract The phototrophic euglenophyte Eutreptiella eupharyngea often causes blooms in the coastal waters of many countries, but its mode of nutrition has not been assessed. This species has previously been considered as exclusively auxotrophic. To explore whether E. eupharyngea is a mixotrophic species, the protoplasm of E. eupharyngea cells were examined using light, epifluorescence, and transmission electron microscopy after eubacteria, the cyanobacterium Synechococcus sp., and diverse algal ...
1 Citations Source Cite
Published on Jan 1, 2019in Algal Research-Biomass Biofuels and Bioproducts 3.75
Sreejith Kottuparambil1
Estimated H-index: 1
(King Abdullah University of Science and Technology),
Roshni Lilly Thankamony6
Estimated H-index: 6
(King Abdullah University of Science and Technology),
Susana Agustí36
Estimated H-index: 36
(King Abdullah University of Science and Technology)
Abstract Microalgae-derived functional materials, such as food supplements, drugs, and biofuels have gained a great deal of attention in recent times. Among the several microalgae investigated for biomaterials production, Euglena spp. are particularly attractive due to their easiness to grow in cultures and the ability to produce numerous bioactive compounds through extremely complex metabolic pathways. The genus Euglena comprises more than 300 species of unicellular, predominantly freshwater fl...
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