The Impact of Granule Density on Tabletting and Pharmaceutical Product Performance
Abstract
The impact of granule densification in high-shear wet granulation on tabletting and product performance was investigated, at pharmaceutical production scale. Product performance criteria need to be balanced with the need to deliver manufacturability criteria to assure robust industrial scale tablet manufacturing processes. A Quality by Design approach was used to determine in-process control specifications for tabletting, propose a design space...
Paper Details
Title
The Impact of Granule Density on Tabletting and Pharmaceutical Product Performance
Published Date
Feb 10, 2017
Journal
Volume
34
Issue
5
Pages
1002 - 1011
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