Clumping factor A, von Willebrand factor‐binding protein and von Willebrand factor anchor Staphylococcus aureus to the vessel wall
Volume: 15, Issue: 5, Pages: 1009 - 1019
Published: May 1, 2017
Abstract
Essentials Staphylococcus aureus (S. aureus) binds to endothelium via von Willebrand factor (VWF). Secreted VWF-binding protein (vWbp) mediates S. aureus adhesion to VWF under shear stress. vWbp interacts with VWF and the Sortase A-dependent surface protein Clumping factor A (ClfA). VWF-vWbp-ClfA anchor S. aureus to vascular endothelium under shear stress.Objective When establishing endovascular infections, Staphylococcus aureus (S. aureus)...
Paper Details
Title
Clumping factor A, von Willebrand factor‐binding protein and von Willebrand factor anchor Staphylococcus aureus to the vessel wall
Published Date
May 1, 2017
Volume
15
Issue
5
Pages
1009 - 1019
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