A live-attenuated influenza vaccine for H3N2 canine influenza virus
Abstract
Canine influenza is a contagious respiratory disease in dogs caused by two subtypes (H3N2 and H3N8) of canine influenza virus (CIV). Currently, only inactivated influenza vaccines (IIVs) are available for the prevention of CIVs. Historically, live-attenuated influenza vaccines (LAIVs) have been shown to produce better immunogenicity and protection efficacy than IIVs. Here, we have engineered a CIV H3N2 LAIV by using the internal genes of a...
Paper Details
Title
A live-attenuated influenza vaccine for H3N2 canine influenza virus
Published Date
Apr 1, 2017
Journal
Volume
504
Pages
96 - 106
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Notes
History