Recent developments in trans-sialidase inhibitors of Trypanosoma cruzi
Abstract
Chagas is a lethal chronic disease that currently affects 8–10 million people worldwide, primarily in South and Central America. Trypanosoma cruzi trans-sialidase is an enzyme that is of vital importance for the survival of the parasite due to its key role in the transfer of sialic acid from the host to the parasite surface and it also helps the parasite combat the host’s immune system. This enzyme has no equivalent human enzyme; thus, it has...
Paper Details
Title
Recent developments in trans-sialidase inhibitors of Trypanosoma cruzi
Published Date
Feb 20, 2017
Journal
Volume
25
Issue
6
Pages
485 - 498
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