Use of Intraarticular Hyaluronic Acid in the Management of Knee Osteoarthritis in Clinical Practice

Knee osteoarthritis (KOA) is a chronic disorder characterized by joint pain, increasing physical disability, and progressive cartilage degeneration, which can lead to total knee arthroplasty (TKA). Despite extensive research, the complex pathophysiology of KOA remains incompletely understood. As a result, no established disease-modifying treatment exists today, and the management of KOA still relies on a combination of nonpharmacologic and...