The role of physical activity in the molecular regulation of colon cancer risk
Published: Sep 1, 2015
Abstract
A strong body of observational evidence supports the notion that physical activity
(PA) is inversely associated with colon cancer (CC) risk. Epigenetic alterations, such
as aberrant DNA methylation, are apparent in the early stages of carcinogenesis.
Recent evidence has suggested that PA can alter DNA methylation patterns in a
variety of tissues. It is not known whether PA can affect DNA methylation patterns in
genes implicated in CC risk....
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