Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

Volume: 12, Issue: 2, Pages: 439 - 451
Published: Feb 1, 2017
Abstract
Historically, it has been difficult to propagate cells in vitro that are derived directly from human tumors or healthy tissue. However, in vitro preclinical models are essential tools for both the study of basic cancer biology and the promotion of translational research, including drug discovery and drug target identification. This protocol describes conditional reprogramming (CR), which involves coculture of irradiated mouse fibroblast feeder...
Paper Details
Title
Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens
Published Date
Feb 1, 2017
Volume
12
Issue
2
Pages
439 - 451
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