Palmitoleic acid reduces the inflammation in LPS‐stimulated macrophages by inhibition of NFκB, independently of PPARs

Volume: 44, Issue: 5, Pages: 566 - 575
Published: Apr 21, 2017
Abstract
Palmitoleic acid (PM, 16:1n-7) has anti-inflammatory properties that could be linked to higher expression of PPARα, an inhibitor of NFκB. Macrophages play a major role in the pathogenesis of chronic inflammation, however, the effects of PM on macrophages are underexplored. Thus, we aimed to investigate the effects of PM in activated macrophages as well the role of PPARα. Primary macrophages were isolated from C57BL/6 wild type (WT) and PPARα...
Paper Details
Title
Palmitoleic acid reduces the inflammation in LPS‐stimulated macrophages by inhibition of NFκB, independently of PPARs
Published Date
Apr 21, 2017
Volume
44
Issue
5
Pages
566 - 575
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