Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts

Volume: 18, Issue: 1, Pages: 21 - 21
Published: Jan 30, 2017
Abstract
Current three-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present Chrom3D, a user-friendly whole-genome 3D computational modeling framework that simulates positions of topologically-associated domains (TADs) relative to each other and to the nuclear periphery. Chrom3D integrates chromosome conformation capture (Hi-C) and lamin-associated domain (LAD)...
Paper Details
Title
Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts
Published Date
Jan 30, 2017
Volume
18
Issue
1
Pages
21 - 21
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