Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster
Abstract
Evolutionary theory predicts that antagonistically selected alleles, such as those with divergent pleiotropic effects in early and late life, may often reach intermediate population frequencies due to balancing selection, an elusive process when sought out empirically. Alternatively, genetic diversity may increase as a result of positive frequency-dependent selection and genetic purging in bottlenecked populations. While experimental evolution...
Paper Details
Title
Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster
Published Date
Jan 14, 2017
Journal
Volume
18
Issue
1
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