Sleeve gastrectomy drives persistent shifts in the gut microbiome

Background Changes in the gut microbiome following bariatric surgery have been causally linked to metabolic benefits. Objectives We sought to characterize and assess the stability of gut microbiome shifts following sleeve gastrectomy (SG). Setting University laboratories. Methods Diet-induced obese mice were randomized to SG or sham surgery. Mice were housed individually or cohoused such that one SG mouse was housed with one weight-matched,...