Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer
Abstract
The role of the Warburg effect in cancer remains to be elucidated with a resurgence in research efforts over the past decade. Why a cancer cell would prefer to use energy inefficient glycolysis, leading to an alteration of pH both inside and outside of the cell, remains to be uncovered. The development of MDR represents a major challenge in the treatment of cancer and it is explained, so far, by the over expression of drug transporters such as...
Paper Details
Title
Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer
Published Date
Apr 1, 2017
Journal
Volume
43
Pages
42 - 48
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