Original paper
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology
Abstract
Plants and many lower organisms, but not mammals, express alternative oxidases (AOX) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping. Thus, they maintain electron flow under conditions when the classical respiratory chain is impaired, limiting excess production of oxygen radicals and supporting redox and metabolic homeostasis. AOX from Ciona intestinalis has been...
Paper Details
Title
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology
Published Date
Jan 1, 2016
Journal
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Notes
History