Highly Sensitive Electrochemical BioMEMS for TNF-α Detection in Humansaliva: Heart Failure

Prediction of disease progression using saliva as a diagnostic medium has roused the interest of scientific researchers in the 10 last past years. Potentially important biomarkers are increased in saliva during local and systemic inflammation. In the present study we have developed a highly sensitive biosensor for TNF-α detection in human saliva of patients suffering from heart failure. Therefore, a fully integrated electrochemical BioMEMS was...