Gold Nanoparticles as Nucleation-Inducing Reagents for Protein Crystallization
Abstract
Protein crystallization is a necessary but time-consuming and difficult step in structure determination by crystallography. The rate-limiting step of crystallization is nucleation, where protein monomers in solution cluster in an ordered fashion to form a stable nucleus. Here, we propose the use of gold nanoparticles to accelerate nucleation and enhance crystal formation. We tested whether gold nanoparticles can facilitate nucleation by...
Paper Details
Title
Gold Nanoparticles as Nucleation-Inducing Reagents for Protein Crystallization
Published Date
Jan 12, 2017
Journal
Volume
17
Issue
2
Pages
497 - 503
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History