Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Abstract
The removal of unwanted or damaged mitochondria by autophagy, a process called mitophagy, is essential for key events in development, cellular homeostasis, tumor suppression, and prevention of neurodegeneration and aging. However, the precise mechanisms of mitophagy remain uncertain. Here, we identify the inner mitochondrial membrane protein, prohibitin 2 (PHB2), as a crucial mitophagy receptor involved in targeting mitochondria for autophagic...
Paper Details
Title
Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Published Date
Jan 1, 2017
Journal
Volume
168
Issue
1-2
Pages
224 - 238.e10
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Notes
History