Pathological changes of adipose tissue in secondary lymphoedema

The pathophysiology of lymphoedema is poorly understood. Current treatment options include compression therapy, resection, liposuction and lymphatic microsurgery, but determining the optimal treatment approach for each patient remains challenging. We characterized skin and adipose tissue alterations in the setting of secondary lymphoedema. Morphological and histopathological evaluations were conducted for 70 specimens collected from 26 female...