Original paper
Elucidation of Signaling Pathways from Large-Scale Phosphoproteomic Data Using Protein Interaction Networks
Abstract
Phosphoproteomic experiments typically identify sites within a protein that are differentially phosphorylated between two or more cell states. However, the interpretation of these data is hampered by the lack of methods that can translate site-specific information into global maps of active proteins and signaling networks, especially as the phosphoproteome is often undersampled. Here, we describe PHOTON, a method for interpreting phosphorylation...
Paper Details
Title
Elucidation of Signaling Pathways from Large-Scale Phosphoproteomic Data Using Protein Interaction Networks
Published Date
Dec 1, 2016
Journal
Volume
3
Issue
6
Pages
585 - 593.e3
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Notes
History