Prediction of Clinical Outcomes in Prenatal Hydronephrosis: Importance of Gravity Assisted Drainage

Published on Mar 1, 2017in The Journal of Urology5.647
· DOI :10.1016/j.juro.2016.09.111
Rachael D. Sussman2
Estimated H-index: 2
(MedStar Georgetown University Hospital),
Emily S. Blum2
Estimated H-index: 2
+ 3 AuthorsHans G. Pohl6
Estimated H-index: 6
Purpose: In infants with SFU (Society for Fetal Urology) grade 3-4 congenital hydronephrosis, 99mTc-mercaptoacetyltriglycine diuretic renography assesses differential function and drainage half-time. We routinely also include the percent of radiotracer drained after 30 minutes of diuresis as well as after 15 minutes with the patient in the upright position. We investigated whether any 1 or more of these parameters on initial diuretic renography predicts persistent or worsening drainage parameters.Materials and Methods: Infants 6 months or younger with grade 3-4 congenital hydronephrosis who presented between January 2009 and December 2014 were identified from billing data and included in analysis if they underwent at least 1 baseline diuretic renography. Those with structural anomalies were excluded from study. Baseline and followup differential function, diuresis half-time, clearance at 30 minutes and clearance with the patient upright were abstracted and comparisons were made between those with initiall...
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