P‐selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin‐1 in mice

Essentials•The main receptor for platelet glycoprotein (GP) Ibα is von Willebrand factor (VWF).•P‐selectin and thrombospondin‐1 (TSP1) have been suggested as counter receptors for GPIbα.•In a laser injury model, P‐selectin promotes thrombus propagation independently of VWF and TSP1.•In a laser injury model, thrombus persists in interleukin‐4 receptor α/GPIbα‐transgenic mice.AcknowledgementsA. Chauhan's laboratory is supported by the following...