Original paper

Mediation analysis for a survival outcome with time‐varying exposures, mediators, and confounders

Volume: 36, Issue: 26, Pages: 4153 - 4166
Published: Aug 15, 2017
Abstract
We propose an approach to conduct mediation analysis for survival data with time-varying exposures, mediators, and confounders. We identify certain interventional direct and indirect effects through a survival mediational g-formula and describe the required assumptions. We also provide a feasible parametric approach along with an algorithm and software to estimate these effects. We apply this method to analyze the Framingham Heart Study data to...
Paper Details
Title
Mediation analysis for a survival outcome with time‐varying exposures, mediators, and confounders
Published Date
Aug 15, 2017
Volume
36
Issue
26
Pages
4153 - 4166
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