A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep
Abstract
Chronic gonadotropin-releasing hormone agonist (GnRHa) administration is used where suppression of hypothalamic-pituitary-gonadal axis activity is beneficial, such as steroid-dependent cancers, early onset gender dysphoria, central precocious puberty and as a reversible contraceptive in veterinary medicine. GnRH receptors, however, are expressed outside the reproductive axis, e.g. brain areas such as the hippocampus which is crucial for learning...
Paper Details
Title
A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep
Published Date
Mar 1, 2017
Journal
Volume
77
Pages
1 - 8
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