Impact of schizophrenia on anterior and posterior hippocampus during memory for complex scenes

Hippocampal dysfunction has been proposed as a mechanism for memory deficits in schizophrenia. Available evidence suggests that the anterior and posterior hippocampus could be differentially affected. Accordingly, we used fMRI to test the hypothesis that activity in posterior hippocampus is disproportionately reduced in schizophrenia, particularly during spatial memory retrieval. 26 healthy participants and 24 patients with schizophrenia from...